Do you think LSD has any benefits?

[RiaX]

@ Synaesthesia

Contact high is a placebo effect.

@ lestoran

5-HT is serotoinin's short hand form. LSD doesnt effect the other monoamines but they will respond through feedback cycles. In terms of the effects it depends on the individual, its elimination half-life (the time it takes for the drug concentration to decrease by half) is 3 - 5 hours according to my pharmacology textbooks.

Yes there is some truth in what you stated. Receptors in the body do not like to be activated constantly, that is the MOA for tolerance. Scientifically the receptors physically flip themselves so that a ligand cannot bind to it.

 

[lestoran]

@ Synaesthesia

@ lestoran

5-HT is serotoinin's short hand form. LSD doesnt effect the other monoamines but they will respond through feedback cycles. In terms of the effects it depends on the individual, its elimination half-life (the time it takes for the drug concentration to decrease by half) is 3 - 5 hours according to my pharmacology textbooks.

Yes there is some truth in what you stated. Receptors in the body do not like to be activated constantly, that is the MOA for tolerance. Scientifically the receptors physically flip themselves so that a ligand cannot bind to it.

Thanks for that. The 3-5 hours half life pretty much refutes that theory.

As a long term medical stimulant user (Ritalin) I'm pretty familiar with receptor tolerance as well as the inverse relationship between dopamine on the one hand and serotonin / acetyl-choline on the other. Did not know that receptors physically flip themselves - will read up more on that.

 

[Skywalker42]

Francis Crick conceived the double helix structure of DNA while on a LSD trip.

'Dick Kemp told me he met Francis Crick at Cambridge. Crick had told him that some Cambridge academics used LSD in tiny amounts as a thinking tool, to liberate them from preconceptions and let their genius wander freely to new ideas. Crick told him he had perceived the double-helix shape while on LSD.

 

[RiaX]

the structure of DNA was not discovered by one person

 

[Chamberz]

I'll tell you an experience i had on LSD, I know first hand that LSD has the potential to unlock certain "mysteries" within the brain circuits. Before i say what im going to im aware that there will be trolls and simple rational naive people who will think "oh ya this guy was just tripping balls" but for those who have an open mind can believe in the possibility. When i was 21 a mate and i got some LSD, particularly a stronger dose than we had ever anticipated, anyhow about 7 hours into the trip i somewhat lost the ability to speak properly and decided to chill on the couch and just be, wchatting to my friend without realising it for a good. what seemed to be 30 mins or so, we had a entire conversation without the use of words, or any human way of communicating. We had somehow slipped into a telepathic link and communicated with our minds. * sounds insane yes but my thoughts he could hear and vice-versa and weirdly we both just shot back up from the couch and asked did that just happen. Like our brainwaves had somehow synced. Weird ****, but just a thought. LsD definitely does unlock hidden brain paths that we as humans have not yet learnt to use.

 

[RiaX]

7 hours into the trip

and thats why pure LSD cant be used in medicine. Impractical

Interesting story was this a good friend ? people who know each other very well can usually tell what the other is thinking and since LSD removes the ability of the brain filling in the gaps its possible you were able to read each other's body language. I highly doubt anything telepathic though.

There was a study done on LSD (mentioned in the documentary I posted up) where people on LSD where able to tell the difference between a picture of a convex and concave face mask. The normal control couldnt as it appeared to look the same. In other words the brain interpreted the information recieved from the optic nerve differently.

Just like those word puzzles you get that go "John has a dig bick ....... yes you read it wrong" or those paragraphs that jumble up the letters and you are still able to read the paragraph as if it was written properly. I highly doubt that anyone on LSD would be caught on that since LSD kind of 'removes' the brain's filter of information. The brain's ability to fill in the gaps in perception is lost, which would also be the cause of its dangers.

 

[Sherbang]

the structure of DNA was not discovered by one person

That's irrelevant, nobody, including Skywalker42, said DNA was discovered by one person.
All he said was that Francis Crick conceived the double helix structure of DNA while on a LSD trip and that he and other Cambridge academics used LSD in tiny amounts as a thinking tool, to liberate them from preconceptions and let their genius wander freely to new ideas - this would be a benefit of lsd that they recognised. It also shatters the preconceived stereotype of the lsd user being an unintelligent hippie who does nothing but 'space out' all day...

 

[Sherbang]

and thats why pure LSD cant be used in medicine. Impractical

Why, because the trip is so long? That's not impractical, it just means different preparation.

I highly doubt that anyone on LSD would be caught on that since LSD kind of 'removes' the brain's filter of information. The brain's ability to fill in the gaps in perception is lost, which would also be the cause of its dangers.

I'd like to see the research that came to this conclusion. And don't just say watch the video, I did already.

 

[syntax]

I'll tell you an experience i had on LSD, I know first hand that LSD has the potential to unlock certain "mysteries" within the brain circuits. Before i say what im going to im aware that there will be trolls and simple rational naive people who will think "oh ya this guy was just tripping balls" but for those who have an open mind can believe in the possibility. When i was 21 a mate and i got some LSD, particularly a stronger dose than we had ever anticipated, anyhow about 7 hours into the trip i somewhat lost the ability to speak properly and decided to chill on the couch and just be, wchatting to my friend without realising it for a good. what seemed to be 30 mins or so, we had a entire conversation without the use of words, or any human way of communicating. We had somehow slipped into a telepathic link and communicated with our minds. * sounds insane yes but my thoughts he could hear and vice-versa and weirdly we both just shot back up from the couch and asked did that just happen. Like our brainwaves had somehow synced. Weird ****, but just a thought. LsD definitely does unlock hidden brain paths that we as humans have not yet learnt to use.

dude, i have watched tree branches grow, seen my ceiling fan go through a decaying process then regenerate completely. The odd thing, my g/f saw the exact same thing. Doesnt make it real though, and although i dont remember it, i probably mentioned what i was seeing to her. And so, she started seeing it to..

Acid can do some crazy things...doesnt make any of it real though

 

[Sensorei]

Chamberz is right. Telepathy is quite common on lsd and I have experienced it, but it only happens with people you trust enough to 'let in your mind'. We've all got someone who's sentences we can finish, or who when you say something will often say they were just about to say that. That is no coincidence, and when you add lsd you can literally communicate by thought and image projection. LSD enhances all your senses dramaticaly, including your 6th sense which we barely notice in every day life since our busy modern lives have completely desensitised us. Huxley wrote a bit about thought transference as did Dr. Grof who was a leading researcher into the effects of lsd back in the day and did quite extensive work with psychedelic therapy. Google him, you might learn a thing or 2. He has 50 years experience in this field. Watch these youtube vid interviews with him.

http://www.youtube.com/watch?v=n-Mi05Ofaqw
http://www.youtube.com/watch?v=5ig3eU_oDS0

Now someone who has taken a few psychedelics will understand this, otherwise of course it would seem entirely impossible, and narrow minded folk like our friendly forum pharmacist would be expected to give their "I highly doubt it" responses.

I had a group of close friends as a student and when we were coming down lsd we would play games like this, thought projecting etc but it does take a few trips to learn how to have some control over it.

 

[RiaX]

So you saying LSD makes you telepathic ?

wooow :wtf:

 

[Sensorei]

It can allow you to transmit information to another person without use of the 5 common senses or any physical interaction. So, yes, but that doesn't mean I'm saying it gives you the ability to read the minds of people who are not completely willing or gives you some ridiculous superpower.

 

[Synaesthesia]

I think we "read each others minds" all the time, just by empathy, thinking what someone is thinking. Most communication is non-verbal, consisting of body language and tone of voice. This is how my dog understands me, (and I also understand his emotions - through body language) LSD just makes you more aware of this, and opens you up to communicating about it. It's an awareness thing.

 

[RiaX]

I think we "read each others minds" all the time, just by empathy, thinking what someone is thinking. Most communication is non-verbal, consisting of body language and tone of voice. This is how my dog understands me, (and I also understand his emotions - through body language) LSD just makes you more aware of this, and opens you up to communicating about it. It's an awareness thing.

Thank you at least someone still remains logical

 

[Sensorei]

No, I am talking about literally thinking about something, eg. riding my bicycle and then asking my friend what am I thinking about and him saying your mountain bike, then thinking about his sister and him saying exactly that. We could go on for ages doing this, asking things there was no way of randomly guessing. Even after we'd come down.

Of course most people won't believe this and I couldn't care less. It's like trying to describe a kaleidoscope to someone who was born blind.

 

[Sherbang]

No, I am talking about literally thinking about something, eg. riding my bicycle and then asking my friend what am I thinking about and him saying your mountain bike, then thinking about his sister and him saying exactly that. We could go on for ages doing this, asking things there was no way of randomly guessing. Even after we'd come down.

Of course most people won't believe this and I couldn't care less. It's like trying to describe a kaleidoscope to someone who was born blind.

Well, unless this was done under experimental conditions, i.e. a double blind randomized controlled trial type thing, your inferences about what went down don't really mean anything. It's well established that subjective experience, even when not under the influence of anything, is misleading and often does not reflect reality. There could be many explanations for your experience that discount telepathy. Magicians do 'telepathy' on stage all the time, it's an illusion...

 

[Happy Camper]

Well, unless this was done under experimental conditions, i.e. a double blind randomized controlled trial type thing, your inferences about what went down don't really mean anything. It's well established that subjective experience, even when not under the influence of anything, is misleading and often does not reflect reality. There could be many explanations for your experience that discount telepathy. Magicians do 'telepathy' on stage all the time, it's an illusion...

Perhaps it was not telepathy, but regardless of 'what it is' the conclusion is that some weird events can and do happen whilst on LSD. I have had a few similar experiences to Sensorei. I am not a religious person, and nor am I prone to fall for mystical events but a few times I have had to sit up and wonder wtf just happened. The human mind truly is a wonderful thing

 

[RiaX]

Magicians do 'telepathy' on stage all the time, it's an illusion...

I learnt card magic and mentalism was pretty good at it too. Used to love watching people try and figure out the tricks and the explainations they would come up with were out of this world.

Someone asked me to do a trick (cause when you do magic and people hear of it the first thing they ask is for a trick), so I learnt a very simple trick with my zippo. Where you appear to take the flame away in your hand and throw it back on the wick. Now all you doing is killing the flame with your fingers and there is a tiny flame on the wick covered by the zippo, so the action of throwing the flame back provides just enough oxygen to restart the flame. The most common explaination was, "you picked up the fire between your fingers" ..... really

 

[AstroTurf]

I could while high and for months after a trip find the last item touched by someone by touching them (just a game, keys, phones, wallets, glasses on a table, tell them to touch something while I am in another room and when I get back I could 100% of the time tell them what it was they touched after touching their arm, hand etc).

Also about 95% right while high and about 80% right for a few weeks after when it came to zener cards.

I also had a bit of intuition when it came to traumatic experiences about to happen.
Sudden urge to leave a club, do so, next day I find out it was raided about 30 minutes later (this happened at 3 different clubs 6 times).

 

[Sensorei]

I could while high and for months after a trip find the last item touched by someone by touching them (just a game, keys, phones, wallets, glasses on a table, tell them to touch something while I am in another room and when I get back I could 100% of the time tell them what it was they touched after touching their arm, hand etc).

Also about 95% right while high and about 80% right for a few weeks after when it came to zener cards.

I also had a bit of intuition when it came to traumatic experiences about to happen.
Sudden urge to leave a club, do so, next day I find out it was raided about 30 minutes later (this happened at 3 different clubs 6 times).

Finally someone on the same wavelength. I know what you mean, we played this game where my mate or I would hide something anywhere in the house (it was a big house) and the other person could literally go to exactly where that item was hidden. It's just like accessing the other persons memory and seeing the mental picture that was stored. Forgot all about that lol.