Every COVID-19 vaccine and treatment in development and on trial, so far.

Gordon_R

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15,989

Gordon_R

Honorary Master
Joined
Jul 5, 2009
Messages
15,989

Gordon_R

Honorary Master
Joined
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Messages
15,989
Encouraging real-world efficacy data from the over-60s phase of Israel's vaccine rollout:
Prof Malka Gorfine, Hagai Rossman, Prof Eran Segal, and Dr Uri Shalit analysed national data by age and city.

They identified bigger falls in infections and hospitalisations both in the over-60s, who were vaccinated first, and in the cities which vaccinated the largest proportion of their populations earliest.

These relative changes were not seen in earlier lockdowns.

This gives early but encouraging signs the falls can be linked to the vaccine, and not just to current restrictions.
Separately, Israel's second-largest healthcare provider Maccabi published figures showing 66 people out of a group of 248,000 vaccinated (0.03%) caught the Covid-19 virus, more than a week after receiving the second dose of the vaccine.

Of those 66, all had mild symptoms and none were hospitalised.
Unlike the MoH, Maccabi compared the infection rate with 900,000 unvaccinated people with a similar demographic profile. In this group during the same time period, 8,250 caught Covid - 11 times as many.

They estimated this meant the vaccine was 92% effective when used in a population - very similar to the 95% Pfizer found in a controlled clinical trial.
 

Gordon_R

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Jul 5, 2009
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Slightly off-topic, but interesting article on the technology behind those fancy glass vials used to package vaccines:
Covid-19 vaccines that use mRNA, such as those made by Pfizer/BioNTech and Moderna, require storage at around -80C. Valor glass can withstand temperatures from between -180C and 400C.

Resistance to extreme heat is useful because pharmaceutical firms wash vials and heat them to around 350C to sterilise them before filling them with products.
 

Gordon_R

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Joined
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Messages
15,989

Gordon_R

Honorary Master
Joined
Jul 5, 2009
Messages
15,989
Side-effects have been rare and mostly minor:
Around 3 in every 1,000 people given the vaccines were affected.

Almost all cases were mild, such as sore arm, tiredness and and 'flu-like' illness.
Severe allergic reactions to the Pfizer/BioNTech vaccine can happen but are very rare - between one and two cases per 100,000 doses administered, experts estimate.
 

Gordon_R

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Joined
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15,989
Approval granted for volunteer human challenge trials, which will study the infection process under highly controlled conditions:
The trials will help scientists work out the smallest amount of coronavirus needed to cause infection, and how the body's immune system reacts to it.
Initially, the study will use the virus that has been circulating in the UK since the pandemic began in March, which is of low risk to healthy adults, to deliberately infect volunteers.

In time, a small numbers of volunteers are likely to be given an approved vaccine and then exposed to the virus, helping scientists to find out the most effective ones.
 
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