Gene found to cause sudden death in young people

[Binary_Bark]

A new gene that can lead to sudden death among young people and athletes has now been identified by an international team of researchers. The gene, called CDH2, causes arrhythmogenic right ventricle cardiomyopathy (ARVC), which is a genetic disorder that predisposes patients to cardiac arrest and is a major cause of unexpected death in seemingly healthy young people.


Identifying the gene responsible for arrhythmogenic right ventricle cardiomyopathy (ARVC) in young people is important because it helps to clarify the genetic mechanisms underlying ARVC, and it also makes the early detection of ARVC possible in otherwise unsuspecting people.
Credit: © DigitalGenetics / Fotolia​

Researchers from Canada, South Africa and Italy have identified a new gene that can lead to sudden death among young people and athletes.

The gene, called CDH2, causes arrhythmogenic right ventricle cardiomyopathy (ARVC), which is a genetic disorder that predisposes patients to cardiac arrest and is a major cause of unexpected death in seemingly healthy young people.

The discovery, published in Circulation: Cardiovascular Genetics, is the result of international collaboration that began 15 years ago. It is led by a South African team headed by Bongani Mayosi, a professor of cardiology at the University of Cape Town and Groote Schuur Hospital, along with researchers of the Italian Auxologico Institute of Milan and the University of Pavia. A team of investigators from the Population Health Research Institute of McMaster University and Hamilton Health Sciences, led by Dr. Guillaume Paré, performed the genetic sequencing, as well as the bioinformatics analysis for the study.

More: https://www.sciencedaily.com/releases/2017/03/170309150637.htm

 

[Suspect99]

http://www.timeslive.co.za/scitech/...overs-killer-heart-gene-in-major-breakthrough. Slightly different angle on the breakthrough