International COVID-19 Updates & Discussion 2

tetrasect

Senior Member
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Aug 22, 2009
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854
I did a bit of quick googling, but can't come to anything conclusive. Everything points to "it's too early to tell".

Yeah obviously it's too early to make any conclusive claims about anything Covid-19 related. This stuff needs years of research to iron out all the details and you never know if something else is at play. No scientist would go out and say "there's 0% chance you can ever get infected again".

However, they have shown that those exposed do produce sars-cov-2 specific T-cells and that those are present long after antibodies have declined, which basically does mean that "most likely" you won't get infected again...
 

zoozi

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Nov 11, 2019
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473
New Evidence Suggests Young Children Spread Covid-19 More Efficiently Than Adults
Two new studies, though from different parts of the world, have arrived at the same conclusion: that young children not only transmit SARS-CoV-2 efficiently, but may be major drivers of the pandemic as well.

The first, which was published in JAMA yesterday, reports findings from a pediatric hospital in Chicago, Illinois. The second, a preprint manuscript awaiting peer review, was conducted in the mountainous province of Trento, Italy.

The Chicago study examines the concentration of the SARS-CoV-2 in the nasopharynx, or the upper region of the throat that connects to the nasal passages, of children and adults. According to the results, children 5 years and younger who develop mild to moderate Covid-19 symptoms have 10 to 100 times as much SARS-CoV-2 in the nasopharynx as older children and adults.
https://www.forbes.com/sites/willia...19-more-efficiently-than-adults/#2542518f19fd

https://jamanetwork.com/journals/jamapediatrics/fullarticle/2768952
https://www.medrxiv.org/content/10.1101/2020.07.16.20127357v1?rss=1
 

"D"

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Oct 20, 2006
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New Evidence Suggests Young Children Spread Covid-19 More Efficiently Than Adults
Where's all the Keep-Schools-OPEN brigad(i)ers now?

Just six months ago:

The virus was originally thought to be spreading from animals to people, but CDC officials now say there is evidence that "limited person-to-person spread is happening." Nine deaths from the virus have been confirmed so far, according to The Associated Press. In addition to the U.S., cases have been reported in China, Thailand, Japan, Taiwan and South Korea.

Last month, patients experiencing fever, cough, and difficulty breathing began cropping up in Wuhan, in central China. More than 275 cases have now been confirmed in China, according to the World Health Organization.

Dr. Nancy Messonnier, director of the CDC's National Center for Immunization and Respiratory Diseases, told reporters Tuesday that news of the first U.S. case "is concerning."

"We expect additional cases in the US," she said.
Feels like lifetimes ago. For some it was.
 
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pinball wizard

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Where's all the Keep-Schools-OPEN brigadiers now?
Huh? we all knew kids get and spread the virus with little to no symptoms themselves. This just confirms that. Keep the schools open and keep the old/infirm away from the kids when they come home.
 

"D"

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Huh? we all knew kids get and spread the virus with little to no symptoms themselves. This just confirms that. Keep the schools open and keep the old/infirm away from the kids when they come home.
What about the masses of infirm kids? Or the multitude of other population segments?
 

pinball wizard

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What about the masses of infirm kids? Or the multitude of other population segments?
Masses? What are you on about? Kids are not dying from this thing anywhere. The problem isn't them and their health.

What population segments? Keep the people with comorbids and old people away from everyone. It's pretty simple, isn't it?
 

MiW

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Sep 18, 2009
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I did a bit of quick googling, but can't come to anything conclusive. Everything points to "it's too early to tell".
We then showed that SARS-recovered patients (n=23) still possess long-lasting memory T cells reactive to SARS-NP 17 years after the 2003 outbreak, which displayed robust cross-reactivity to SARS-CoV-2 NP. Surprisingly, we also frequently detected SARS-CoV-2 specific T cells in individuals with no history of SARS, COVID-19 or contact with SARS/COVID-19 patients (n=37). SARS-CoV-2 T cells in uninfected donors exhibited a different pattern of immunodominance, frequently targeting the ORF-1-coded proteins NSP7 and 13 as well as the NP structural protein.

That is the best study I've seen.
 

Geoff.D

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Aug 4, 2005
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Huh? we all knew kids get and spread the virus with little to no symptoms themselves. This just confirms that. Keep the schools open and keep the old/infirm away from the kids when they come home.
Ja nothing new, just someone now has got around to sorting the details out into a hopefully properly peer-reviewed publication.
 

OrbitalDawn

Ulysses Everett McGill
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Aug 26, 2011
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Novavax, the little-known Maryland company that received a $1.6 billion deal from the federal government for its experimental coronavirus vaccine, announced encouraging results in two preliminary studies on Tuesday.

In one study, 56 volunteers produced a high level of antibodies against the virus without any dangerous side effects. In the other, researchers found that the vaccine strongly protected monkeys from coronavirus infections.

Although it’s not possible to directly compare the data from clinical trials of different coronavirus vaccines, John Moore, a virologist at Weill Cornell Medicine who was not involved in the studies, said the Novavax results were the most impressive he had seen so far.
 

hexagon

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May 31, 2006
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457

That is the best study I've seen.
Yes. The study and T-cell cross-reactivity are discussed further here and here.
 
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