International COVID-19 Updates & Discussion 3

Paulsie

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It seems that is well known factor from flu vaccinations, just no one is hyping it in the media.
Because no one is allowed any comment deemed negative. In fact no one is allowed to comment full stop.
 

Geoff.D

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Interesting that they only picked this up now, clearly the phase 3 studies were not very thorough. Not that half the antibodies means differences in clinical outcomes, or vaccine effectiveness.
Pretty obvious from the info available on obese people being more severely affected by the virus.
 

Gordon_R

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Pretty obvious from the info available on obese people being more severely affected by the virus.

Completely unrelated. Antibodies reflect the immune system. Co-morbidities reflect the cardio-vascular system. It is possible for asymptomatic cases to be morbidly obese, and very sick people to have no co-morbidity.
 

Paulsie

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Completely unrelated. Antibodies reflect the immune system. Co-morbidities reflect the cardio-vascular system. It is possible for asymptomatic cases to be morbidly obese, and very sick people to have no co-morbidity.
Still, vast majority of casualties and stress on hospitals were caused by those with comorbities. The vaccines were developed to protect those most at risk (old and comorbities), yet those are the groups where vaccines are not as effective.

Long story short, the vaccines will be most effective in those, who don't really need it in the first place. Which actually makes sense as whether your immune system is challenged by the real thing or a vaccine, it is the response of your immune system that counts in the end.
 

Gordon_R

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Both Pfizer and AZ vaccines are very effective at reducing hospitalisation of the elderly in England:
Professor Jonathan Van-Tam, England's deputy chief medical officer, said the decision to give the AstraZeneca vaccine to older people was "clearly vindicated" - some European nations have refused to give it to the over 65s because data from the trials was mainly on its effect among younger adults.
 

MiW

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Both Pfizer and AZ vaccines are very effective at reducing hospitalisation of the elderly in England:
The PHE data also suggests the Pfizer vaccine, which started being rolled out a month before the AstraZeneca vaccine, leads to an 83% reduction in deaths from Covid.

And it shows vaccination cuts the risk of people over 70 developing any Covid symptoms by around 60% three weeks after a first dose.

So no hospitalisations , straight to 17% death
 

MiW

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News of the B1351 variant came just a day after the government began the Philippines vaccination programme using 600,000 shots donated by China.
It remains unknown how effective Sinovac, which has been tested in countries including Brazil, Turkey and Indonesia, will be against the new variant.
Details of the Sinovac trials have not yet been made public by the Philippine government, citing confidentiality, which has raised concern among health watchdogs and healthcare workers.
Dr Legaspi was given the jab despite an earlier statement by the country’s Food and Drug Administration that the Sinovac shot was not recommended for healthcare workers directly involved with COVID-19 patients, or people of 65 years old or more.
As the vaccines were administered to several officials on Monday, other healthcare workers staged a demonstration outside the Philippine Lung Center to demand more transparency about the Sinovac shots, as well as more choices on vaccine brands.
The roll-out of the vaccine in the Philippines has been rife with controversy after it was revealed that members of President Rodrigo Duterte’s security detail were vaccinated with Sinopharm shots smuggled from China as early as October of last year.
 

flytek

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You mean the second wave of a stronger mutation has reached more people? Just like us? Or do you have relevant data proving what percentage were reinfected?
 

MiW

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You mean the second wave of a stronger mutation has reached more people? Just like us? Or do you have relevant data proving what percentage were reinfected?

How is this changing the outcome -not reaching herd immunity?

Closed the articles , something like they never got period without cases, 'this is still the first wave' ..a hospital never managed to drop under 40 patients with covid for entire year, 35% of current cases are UK, SA mutations.
 
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flytek

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well that is an interesting discussion requiring data ideally. If people only get reinfected at a tiny rate then there is some form of immunity...does it last? how long? is the same true for vaccine immunity? etc. "no immunity achieved" seems possible although very unlikely...more likely is some immunity achieved but for how long and to what extent.
 

MiW

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well that is an interesting discussion requiring data ideally. If people only get reinfected at a tiny rate then there is some form of immunity...does it last? how long? is the same true for vaccine immunity? etc. "no immunity achieved" seems possible although very unlikely...more likely is some immunity achieved but for how long and to what extent.
Forgot to mention that doctors were complaining of overworking , over filled hospitals and exhaustion.. so not a small %
 

Paulsie

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Lombardy going strong second year ... no immunity achieved

View attachment 1029388
Why would they, when they went through similar lockdowns? They slow the rate of infection (remember?) so that not everybody would have yet been exposed.

Having said that and based on previous indications, it generally takes 2 years for a virus to burn through a population. It will therefore be interesting to see numbers towards the end of this year. Although that will get skewed by the vaccines.
 

MiW

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Why would they, when they went through similar lockdowns? They slow the rate of infection (remember?) so that not everybody would have yet been exposed.

Having said that and based on previous indications, it generally takes 2 years for a virus to burn through a population. It will therefore be interesting to see numbers towards the end of this year. Although that will get skewed by the vaccines.
I think close to 0.3% of the population there died , starting to think that for 'herd immunity 0.5-1% of the population will be gone, depending on demographics and health care.
 

Paulsie

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I think close to 0.3% of the population there died , starting to think that for 'herd immunity 0.5-1% of the population will be gone, depending on demographics and health care.
That would equate with the currently held "99.5% survivability rate" and 70-100% of population having been infected.
 

Gordon_R

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Two significant developments in the US:
The president said that drug manufacturer Merck - which this year discontinued work on its own vaccine - would now be helping Johnson & Johnson to produce its newly approved one-shot drug.

"We're now on track to have enough vaccine supply for every adult in America by the end of May," he said, adding it was "the type of collaboration between companies we saw in World War Two".
The governor of Texas on Tuesday issued an executive order, effective from 10 March, that rescinds most of the coronavirus measures he imposed earlier in the pandemic.

Greg Abbott lifted the regulation ordering people to wear masks and said businesses would be allowed to resume full capacity next week.

"It is now time to open Texas 100%," the Republican said. "Too many small business owners have struggled to pay their bills. This must end."
 
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