Geoff.D
Honorary Master
- Joined
- Aug 4, 2005
- Messages
- 26,878
What does vaccine efficacy mean?
Vaccine efficacy measures the percentage reduction of a disease in a clinical trial. Vaccine effectiveness measures how well a vaccine works in the real world.
Vaccine efficacy is the percentage reduction in a disease in a group of people who received a vaccination in a clinical trial. It differs from vaccine effectiveness, which measures how well a vaccine works when given to people in the community outside of clinical trials.
Very few vaccines are 100% effective. But many routine vaccines have very high levels of effectiveness.
For example, the MMR vaccineTrusted Source is up to 97% effective against measles and 88% effective against mumps, and about 97% effective against rubella.
The annual flu shot has an effectiveness of 40–60%Trusted Source.
Some people may not develop full protection despite receiving a vaccine. Other people are unable to have certain vaccines. This may be because they have an allergy to components in the vaccine or because of other health matters, such as taking immunosuppressant medication.
