International COVID-19 Updates & Discussion 3

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flippakitten

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The peer reviewed study didn't say anything about side effects such as heart inflammation, VITT, and other serious issues. I doubt you even read it yourself

The intro to the podcast should have been the first clue it's probably padded with a lot of nonsense. So much so I'm not even going to waste the 9 minutes of my life.

Reading the study, I have no clue what the implications on human physiology would be but it's very easy to see this is the beginning of a much longer and detailed study, which is a good thing.

Let's face it a study of 11 nurses in one hospital tells you nothing at all.
 

NarrowBandFtw

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Because you did post fake Covid news, and if it is still an offence I’d be interested in the viewpoint of the mods or admin if you continue to do so.
I didn't and your opinion makes no difference to the fact that I didn't, no amount of biased mental gymnastics changes a peer reviewed research paper into fake news no matter how much you wish it.

The height of hypocrisy to make such a charge when you run off to such respected news outlets as ... byrambridle.com ... :ROFL: :ROFL: :ROFL:
 

Paulsie

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WHAT DID HE GET WRONG?​

When Bridle claims “… we never knew the spike protein itself was a toxin and was a pathogenic protein. So by vaccinating people we are inadvertently inoculating them with a toxin …” he is fundamentally incorrect for multiple reasons.

First and foremost, there is no spike protein in the vaccine. But if we assume he means the spike proteins created by your cells are toxic, then he's suggesting that:

  1. The spike protein is distributed throughout the body, and accumulates in tissues and organs.
  2. The spike protein is inherently toxic, and is capable of damaging these tissues.

BRIDLE CLAIMS ...​

... the spike protein accumulates in the spleen, in the liver, in bone marrow, and the adrenal glands ...

... the spike protein accumulates in breast milk, and in the blood.

BUT THE SPIKE PROTEIN DOES NOT ACCUMULATE THROUGHOUT THE BODY​

Bridle claims he has gained access (through a FOI request to the Japanese government) to a new bio-distribution study that demonstrates (for the first time ever!) the distribution of the mRNA vaccines in the body. An image of the relevant table being circulated is presented below. This is untrue (or at least, very misleading) for several reasons.
  1. There are exisiting bio-distribution studies.
  2. The PMDA source document has been available publically for months, and was considered in the European Medicines Agency assessment of the vaccines.
  3. The experiment was conducted in rats, not in humans.
  4. The results are presented by Bridle and his proponents as to suggest the experimenters were measuring concentration and accumulation of spike protein; they were actually measuring tagged lipid-nanoparticles representing the mRNA vaccine.
  5. There are multiple studies demonstrating the vaccine and associated antibodies don't pass through breast milk.

THE PRESENTED TABLE ...​

... is about mRNA, not the spike protein (despite the conflation in the interview) ...

... was conducted in rats ...

... and has the ovaries highlighted to alarm readers.

A page of the PMRA study showing distribution of the lipid-nanoparticle mRNA in rats. The text is in Japanese, and the ovaries row is highlighted.

This is the image being circulated. The original report is here, and a translated version (source of translation unclear) is here.
Notice how the result is highlighted (and often presented as a measurement of spike protein) to alarm, despite evidence demonstrating the vaccine has no effect on ovarian function. Though, if you look to the right for context (conveniently not highlighted by those who circulate the image) the accumulation in the ovaries represents at peak 0.095% (that’s 0.00095 of the dose) of the mRNA injected. Remember, the vaccine – not the spike protein.

BRIDLE CLAIMS ...​

... the spike is toxic, and causes clotting or bleeding ...

... and the spike protein can cross the blood brain barrier and affect the brain.

BUT THE SPIKE PROTEIN PRODUCED BY YOUR CELLS IS NOT IN THE SAME FORM OR CONCENTRATION AS THE VIRAL PROTEIN​

There are two important facts about the spike protein Bridle is ignoring:
  1. The spike protein created by your cells is not the same as the viral spike protein; it has been modified to remain attached to the surface of your cells (so it doesn't freely circulate in the blood), and has been inactivated to further reduce binding to ACE2 receptors.
  2. There concentration of spike protein created by your cells is 100,000x lowerthan the level of viral spike protein shown to cause harm (this is the 11/13 healthcare workers study).
And while Bridle continues to make claims of toxicity, it's not clear if he actually believes that; afterall, he received $230,000 from the Ford (provincial) government to develop a competing vaccine using the same spike protein he claims is toxic. Notably, he expects his vaccine to be ready in 2 - 4 years; it's unclear if his vaccine will be necessary given the safety and efficacy of current vaccines.

BRIDLE CLAIMS ...​

... "looking into the adverse event database in the United States, we have found evidence of suckling infants experiencing bleeding disorders in the gastrointestinal tract" ...

BUT VAERS ACCEPTS ALL CLAIMS AND DOES NOT DEMONSTRATE CAUSALITY​

The Vaccine Adverse Event Reporting System (VAERS) is a United States government program that collects reports of adverse effects (possible side effects) following vaccination. Canada's equivalent program, the (Canadian Adverse Events Following Immunization Surveillance System) CAEFISS, collects reports of adverse effects in Canada, and incorporates active surveillance to further increase the sensitivity of the system.
Both of these systems allow anyone – doctors, nurses, and the public – to submit reports of adverse effects. This makes the system incredibly sensitive, but it means reports can be missing data, can lack detail, and can contain unintentional (and sometimes intentional) errors. In summary, we cannot determine from these reports that the vaccine caused the reported adverse event.
Bridle's appeal to VAERS without providing context is a common anti-vaccine trope. This article describes the practice in the context of Tucker Carlson's recent vaccine disinformation statements.
For more context, John Oliver's latest video on vaccine misinformation explores the practice of appealing to VAERS, and the tactic of repeatedly "raising concerns" or "just asking questions" from a position of authority without providing answers.
If you'd like to review the data yourself, CAEFISS makes available detailed weekly reports – including visualizations – of the adverse events reported in Canada. If you'd like to learn more about the other parts of Canada's extensive vaccine safety systems, you can do so here, courtesy of the Canadian Paediatric Society. You can also review VAERS data here.

I always thought the quality of links provided (or otherwise) gets taken seriously on this forum.

Now, I'm not actually challenging the information used in these links (as I am not competent enough to collaborate), but what I've observed is this:

- Byrambridle.com is the most disgusting and subterfuge attempt at discrediting a person I've ever seen
- the website doing the bidding actually used the person's full name as the website name itself (is it even legal???)
- there is no "about us", no contact details, no address, no names, only blank, generic send a message form
- the website content is copyrighted to a "concerned scientist" - so this somebody is not prepared to stand for what they publish??
- even the Twitter linked to this account was created on May, using the guys full handle @byrambridle (not expecting for Twitter to take this down anytime soon)

Oh how low we have sunk......
 
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Geoff.D

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The intro to the podcast should have been the first clue it's probably padded with a lot of nonsense. So much so I'm not even going to waste the 9 minutes of my life.

Reading the study, I have no clue what the implications on human physiology would be but it's very easy to see this is the beginning of a much longer and detailed study, which is a good thing.

Let's face it a study of 11 nurses in one hospital tells you nothing at all.
A study of 11 nurses that finds issues says there are issues that need attention and at least more investigation. So, you can't say it tells you nothing at all.
 

Daveogg

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A study of 11 nurses that finds issues says there are issues that need attention and at least more investigation. So, you can't say it tells you nothing at all.
I read the article and found it fascinating and a great affirmation of the mRna vaccines. What I don't understand is the "issue" that was found.
My understanding from the study is mRna vaccine is injected, within 1 day, mRNA have been translated into vaccine spike protein, detected by an incredibly sensitive assay. This protein peaks at day 8 and then is eliminated as IgG and IgA antibodies to the spike are produced. On the second dose of the vaccine no spike protein is detected suggesting the antibodies induced by the first dose neutralise the protein before it reaches a level of detection.
I could be wrong but this would be exactly what was hoped would happen?
 

C4Cat

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A study of 11 nurses that finds issues says there are issues that need attention and at least more investigation. So, you can't say it tells you nothing at all.
What issues were found? I just read the paper that was posted earlier, again, and didn't see any mention of any 'issues' other than the small sample size and potential biases that result from enrolling healthy, young adults. The mechanisms underlying release of free S1 and the subsequent detection of the intact spike protein remain unclear and require further studies - is the only thing I could find that relates to your assertion that further investigation is required.
 

Geoff.D

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I read the article and found it fascinating and a great affirmation of the mRna vaccines. What I don't understand is the "issue" that was found.
My understanding from the study is mRna vaccine is injected, within 1 day, mRNA have been translated into vaccine spike protein, detected by an incredibly sensitive assay. This protein peaks at day 8 and then is eliminated as IgG and IgA antibodies to the spike are produced. On the second dose of the vaccine no spike protein is detected suggesting the antibodies induced by the first dose neutralise the protein before it reaches a level of detection.
I could be wrong but this would be exactly what was hoped would happen?
My issue is about someone writing off any study using the generalisation "tells us nothing at all". Every study tell us something. Even if it just reaffirms previous knowledge, it is telling us something.
So my challenge was not about the detail but about how easily people are prepared to reject anything that does not fit their views. We are all guilty of the above at times.
So my interest in this study is now sufficiently stimulated to go and read the detail.
And try to absorb it given I am not an expert in the field.
 

Paulsie

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My issue is about someone writing off any study using the generalisation "tells us nothing at all". Every study tell us something. Even if it just reaffirms previous knowledge, it is telling us something.
So my challenge was not about the detail but about how easily people are prepared to reject anything that does not fit their views. We are all guilty of the above at times.
So my interest in this study is now sufficiently stimulated to go and read the detail.
And try to absorb it given I am not an expert in the field.
Here is the ACTUAL study in question.... Includes downloadable pdf

Edit: apologies @NarrowBandFtw already posted yesterday, but might have got lost in the challenge of the video site link
 

Paulsie

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So his peers would be others in veterinary medicine?

We might be related to monkeys but I think I’ll stick to studies done by doctors and scientists who specialise in human diseases.
By the way and as a late add on - just discovered that the Canadian government must also be a bunch of kooks and covidiots, since he was one of many to be awarded 230,000CAD towards studying and developing covid vaccine. This was back in May 2020.
What were they thinking!!!
 

flippakitten

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My issue is about someone writing off any study using the generalisation "tells us nothing at all". Every study tell us something. Even if it just reaffirms previous knowledge, it is telling us something.
So my challenge was not about the detail but about how easily people are prepared to reject anything that does not fit their views. We are all guilty of the above at times.
So my interest in this study is now sufficiently stimulated to go and read the detail.
And try to absorb it given I am not an expert in the field.

Read the sentence above the 5 words you misquoted.
 

flippakitten

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My issue is about someone writing off any study using the generalisation "tells us nothing at all". Every study tell us something. Even if it just reaffirms previous knowledge, it is telling us something.
So my challenge was not about the detail but about how easily people are prepared to reject anything that does not fit their views. We are all guilty of the above at times.
So my interest in this study is now sufficiently stimulated to go and read the detail.
And try to absorb it given I am not an expert in the field.

The paper makes absolutely no mention of anything the Doctor is claiming and the only other study he mentions has yet to be reviewed.

This is one of those things to watch but it's far too early to be worried (or maybe too late considering I got me first jab :p )
 

Paulsie

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I read the article and found it fascinating and a great affirmation of the mRna vaccines. What I don't understand is the "issue" that was found.
My understanding from the study is mRna vaccine is injected, within 1 day, mRNA have been translated into vaccine spike protein, detected by an incredibly sensitive assay. This protein peaks at day 8 and then is eliminated as IgG and IgA antibodies to the spike are produced. On the second dose of the vaccine no spike protein is detected suggesting the antibodies induced by the first dose neutralise the protein before it reaches a level of detection.
I could be wrong but this would be exactly what was hoped would happen?
From what I understand, the issue is that the assembled spike protein is supposes to bind to cells at the injection site, which in turn starts up the immune system to produce antibodies.

Yet, in some cases, it seems to escape and is found to be floating around the body, which can cause damage (bleeding, clots, brain etc...)??
 

Markd

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By the way and as a late add on - just discovered that the Canadian government must also be a bunch of kooks and covidiots, since he was one of many to be awarded 230,000CAD towards studying and developing covid vaccine. This was back in May 2020.
What were they thinking!!!

so he has a conflict of interest then, doesn't he?
 

Pineapple Smurf

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So this vaccine can improve eyesight? Sign me up. Hopefully making the lower half of the face turn into a void is merely a temporary symptom.
Where the **** did anyone say the vaccine can improve eyesight? Have you been day drinking again?
 

Daveogg

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From what I understand, the issue is that the assembled spike protein is supposes to bind to cells at the injection site, which in turn starts up the immune system to produce antibodies.

Yet, in some cases, it seems to escape and is found to be floating around the body, which can cause damage (bleeding, clots, brain etc...)??
Ok but, there is no evidence, fully assembled spike, or the S1 cleavage is an endotoxin, that's a thumb suck.

Even if it is, circulating spike concentration is logarithmic orders of magnitude less following vaccination than infection and you are going to either be vaccinated or infected.

VITT is antibody mediated not antigen, in fact a diagnostic criteria for VITT is presence of a PF4 antibody.

Lastly if the vaccine is toxic why are we not seeing the cases. I've seen one adverse reaction from the vaccine - an old lady who clearly had been vaccinated below her deltoid and presented with a cellulitis over the vaccine site.
 

Geoff.D

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By the way and as a late add on - just discovered that the Canadian government must also be a bunch of kooks and covidiots, since he was one of many to be awarded 230,000CAD towards studying and developing covid vaccine. This was back in May 2020.
What were they thinking!!!
The joke is on one assignment in Africa in a very remote place, the ONLY remotely available medical expertise was the local Vet. He used to treat animals through the front door and run a human practice through a side door.
 

Paulsie

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Ok but, there is no evidence, fully assembled spike, or the S1 cleavage is an endotoxin, that's a thumb suck.

Even if it is, circulating spike concentration is logarithmic orders of magnitude less following vaccination than infection and you are going to either be vaccinated or infected.

VITT is antibody mediated not antigen, in fact a diagnostic criteria for VITT is presence of a PF4 antibody.

Lastly if the vaccine is toxic why are we not seeing the cases. I've seen one adverse reaction from the vaccine - an old lady who clearly had been vaccinated below her deltoid and presented with a cellulitis over the vaccine site.
You obviously know far more on the subject so I cannot argue, however these negatives seem to crop up among younger population, that has not yet been exposed to vaccines en mass.

Also VAERS has already reported over 5000 deaths, far far more than what in the past would have been an automatic signal to pause and investigate.

And yes I know VAERS is voluntary and inaccurate, but it has always been recognized as a sufficient early warning system
 
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