mRNA Spike protein is very dangerous, it's cytotoxic - says INVENTOR of mRNA Technology

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Hush9300

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It is very difficult to argue with someone who's mind is already made up. We are not talking about stopping this disease - we are talking about lowering all the risks associated with its continued spread, including the unnecessary death of others, various Covid-19 side effects, and of course the emergence of new variants, which we know vaccines will help with.
That's the point... We don't know if vaccines will prevent more virulent variants or if it will give rise to more virulent variants. What we do know is that the virus has remained rather stable in terms of virulence without the presence of vaccines.

I am not arguing that people shouldn't be vaccinated. I am arguing that these vaccines be used in the elderly and the vulnerable while the rest get on with acquired infection for various reasons.

I am not familiar with the discussion around ADE, but my brief review of material over lunch shows while this is a risk, as with many other treatments, it's about weighing up the benefits vs the costs, and the costs appear to be lower than we have to lose. I'll need to read up more on this particular point before I can properly respond to it.
SARS CoV vaccines have a history of disease enhancement but let's be clear the phenomena is not only due to vaccinations. It happens with natural infections too. The problem is that governments are looking to vaccinate just about everybody which may exacerbate the fallout should disease enhancement indeed become a thing.
 
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SoldierMan

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There’s the little soldier boy just posting rumours again…

Will find that Japanese study for you. It was by Pfizer themselves you nutjob.
Rumours indeed :ROFL:

COVID-19 RNA Based Vaccines and the Risk of Prion Disease

ABSTRACT Development of new vaccine technology has been plagued with problems in the past. The current RNA based SARSCoV-2 vaccines were approved in the US using an emergency order without extensive long term safety testing. In this paper the Pfizer COVID-19 vaccine was evaluated for the potential to induce prion-based disease in vaccine recipients. The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma (FUS) into their pathologic prion conformations. The results indicate that the vaccine RNA has specific sequences that may induce TDP-43 and FUS to fold into their pathologic prion confirmations. In the current analysis a total of sixteen UG tandem repeats (ΨGΨG) were identified and additional UG (ΨG) rich sequences were identified. Two GGΨA sequences were found. Potential G Quadruplex sequences are possibly present but a more sophisticated computer program is needed to verify these. Furthermore, the spike protein, created by the translation of the vaccine RNA, binds angiotensin converting enzyme 2 (ACE2), a zinc containing enzyme. This interaction has the potential to increase intracellular zinc. Zinc ions have been shown to cause the transformation of TDP-43 to its pathologic prion configuration. The folding of TDP-43 and FUS into their pathologic prion confirmations is known to cause ALS, front temporal lobar degeneration, Alzheimer’s disease and other neurological degenerative diseases. The enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the RNA based vaccines for SARS-CoV-2 was premature and that the vaccine may cause much more harm than benefit.
 
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VicB

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Any dissenting opinion on something that the powers that be have laid down and you bunch of sycophants pounce on them like they have leprosy or just put the moves on your wife. Quite pathetic and quite worrying. When has censorship ever served humanity in a good way.


When has censorship ever served humanity in a good way.
There's plenty of examples the world over, but let's make it practical.

Why do we not let drunk people drive on the roads? Because it's dangerous for themselves and other road users. It's censorship by sobriety if you will.

Why do we only allow people with licenses to practice medicine? Law? Drive on the road? It's to protect people from themselves and others with regards to them making mistakes and /or uninformed decisions with potentially hazardous outcomes. Censorship by competency if you will.

Information in this day and age is extremely powerful. The power of the pen is mightier than the sword and all that. One can argue that the person with a wide audience or following can be much more influential or damaging than a single person with a gun, and yet people are allowed to use social media and the internet without any restriction, but to own a gun you must show competency and have a license. Just as what information can be used for good, so too can it be used in extremely harmful ways. The incitement of looting this week by a handful of people is a very good example.

And before anyone calls me any names, I am not advocating for censorship in general that prevents people from expressing their opinion. But I am most certainly against people spreading false information knowingly or unknowingly, that can have severe consequences. Even more so against people purposefully spreading harmful information.

Many in this and other threads have cried about Youtube removing content from known conspiracy theorists and anti-vaxxers, calling it censorship. It's not censorship, your not preventing that person from having his opinion, your just preventing him from using said platform to cause harm. Should we allow the Taliban to put videos on Youtube that teaches kids how to make bombs? Isn't that censorship too?

People are very quick on the "censorship is bad" bandwagon, but we do it all the time in many different forms. And people are fine with it, because they understand the relevance and need for it. Nobody is crying out "my body, my rules" when you tell a 14 year old that they can't buy alcohol. They understand why it's necessary.
 
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Chris_SA

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giphy.gif
 

Bryn

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Will find that Japanese study for you. It was by Pfizer themselves you nutjob.
Rumours indeed :ROFL:

COVID-19 RNA Based Vaccines and the Risk of Prion Disease

ABSTRACT Development of new vaccine technology has been plagued with problems in the past. The current RNA based SARSCoV-2 vaccines were approved in the US using an emergency order without extensive long term safety testing. In this paper the Pfizer COVID-19 vaccine was evaluated for the potential to induce prion-based disease in vaccine recipients. The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma (FUS) into their pathologic prion conformations. The results indicate that the vaccine RNA has specific sequences that may induce TDP-43 and FUS to fold into their pathologic prion confirmations. In the current analysis a total of sixteen UG tandem repeats (ΨGΨG) were identified and additional UG (ΨG) rich sequences were identified. Two GGΨA sequences were found. Potential G Quadruplex sequences are possibly present but a more sophisticated computer program is needed to verify these. Furthermore, the spike protein, created by the translation of the vaccine RNA, binds angiotensin converting enzyme 2 (ACE2), a zinc containing enzyme. This interaction has the potential to increase intracellular zinc. Zinc ions have been shown to cause the transformation of TDP-43 to its pathologic prion configuration. The folding of TDP-43 and FUS into their pathologic prion confirmations is known to cause ALS, front temporal lobar degeneration, Alzheimer’s disease and other neurological degenerative diseases. The enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the RNA based vaccines for SARS-CoV-2 was premature and that the vaccine may cause much more harm than benefit.
Well that took about 15 seconds:

 

SoldierMan

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There’s the little soldier boy just posting rumours again…

Pfizer Bio-Distribution Study Submitted to the Japanese Government

  • Canadian immunologist and vaccine researcher Byram Bridle, Ph.D., has gained access to Pfizer’s biodistribution study from the Japanese regulatory agency. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines
  • The assumption that vaccine developers have been working with is that the mRNA in the vaccines would primarily remain in and around the vaccination site. Pfizer’s data, however, show the mRNA and subsequent spike protein are widely distributed in the body within hours
  • This is a serious problem, as the spike protein is a toxin shown to cause cardiovascular and neurological damage. It also has reproductive toxicity, and Pfizer’s biodistribution data show it accumulates in women’s ovaries
  • Once in your blood circulation, the spike protein binds to platelet receptors and the cells that line your blood vessels. When that happens, it can cause platelets to clump together, resulting in blood clots, and/or cause abnormal bleeding
  • Pfizer documents submitted to the European Medicines Agency also show the company failed to follow industry-standard quality management practices during preclinical toxicology studies and that key studies did not meet good laboratory practice standards

Source
 
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SoldierMan

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Well that took about 15 seconds:


So they can tell that after only a year of vaccinations, how do they know this.

It will take time for these effects to occur.

But I like the fact that they got a Pfizer spokesperson to respond. No bias there.....

A Pfizer spokesperson said: “There is no evidence” when asked by Reuters whether its mRNA COVID-19 vaccine had the potential to lead to Alzheimer’s and other neurodegenerative diseases.
 
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SoldierMan

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But hey, let's shut down all debate on an EXPERIMENTAL mRNA vaccine that was only put into use in 2020.

What could possibly go wrong......
 

SoldierMan

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There’s the little soldier boy just posting rumours again…

Horrifying study reveals mRNA vaccine nanoparticles are circulated throughout the entire body: Brain, heart, liver, ovaries, testes and more


The study reveals how mRNA LNPs are distributed across the body, even affecting ovaries and testes, raising huge questions about fertility in those receiving mRNA vaccine shots. The following chart shows the mass of NLPs (in micrograms) found in each organ following mRNA vaccination. Notice how it attacks the adrenals?

pfizer-mrna-biodistribution-study-1.png
 

Conack

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Are you talking to yourself while looking in a mirror?

You posted fake crap from YouTube and even after it’s shown to be fake you double down by repeating it after a couple of pages of comments.

you’re a dangerous nut job, and @rpm should be ashamed for giving you a platform.

More calls for deplatforming and censoring. Disgusting.

-Play the ball, not the man.
If you don't want to play either, ignore him then. The constant call for daddy to censor/deplatform/ban people is some dystopian ****.
 
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SoldierMan

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There’s the little soldier boy just posting rumours again…

But yeah it's all just rumours my good little Brown Shirts, heil Fauci and the WHO!

The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice

Abstract​

It is unclear whether severe acute respiratory syndrome coronavirus 2, which causes coronavirus disease 2019, can enter the brain. Severe acute respiratory syndrome coronavirus 2 binds to cells via the S1 subunit of its spike protein. We show that intravenously injected radioiodinated S1 (I-S1) readily crossed the blood–brain barrier in male mice, was taken up by brain regions and entered the parenchymal brain space. I-S1 was also taken up by the lung, spleen, kidney and liver. Intranasally administered I-S1 also entered the brain, although at levels roughly ten times lower than after intravenous administration. APOE genotype and sex did not affect whole-brain I-S1 uptake but had variable effects on uptake by the olfactory bulb, liver, spleen and kidney. I-S1 uptake in the hippocampus and olfactory bulb was reduced by lipopolysaccharide-induced inflammation. Mechanistic studies indicated that I-S1 crosses the blood–brain barrier by adsorptive transcytosis and that murine angiotensin-converting enzyme 2 is involved in brain and lung uptake, but not in kidney, liver or spleen uptake.


Pfizer/BioNTech animal trials show dangerous concentrations of nano-particles in organs


A study from Nature Neuroscience showed that the S1 spike protein of SARS-CoV-2 crosses the blood–brain barrier in mice, causing damage to the cardiovascular and central nervous systems. The spike protein ended up in the peripheral tissues – thus SARS-CoV-2 RNA was recovered from cerebrospinal fluid.

The study showed that these new spike proteins exploit angiotensin-converting enzyme 2 (ACE2), allowing for increased intake of spike proteins into the lungs and specifically to the brain. This is how SARS-CoV-2 manifests in the central nervous system, which include changes to taste and smell, headaches, twitching, seizures, confusion, vision impairment, nerve pain, dizziness, impaired consciousness, nausea, hemiplegia, ataxia, stroke and cerebral hemorrhage.

Spike proteins readily cross the blood-brain barrier through a process called adsorptive transcytosis. Inflammation notably increases spike protein uptake in the brain and lungs. And when the animals were induced with inflammation, the intravenously-administered spike proteins entered the brain more readily.
 

DA-LION-619

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But yeah it's all just rumours my good little Brown Shirts, heil Fauci and the WHO!

The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice

Abstract​

It is unclear whether severe acute respiratory syndrome coronavirus 2, which causes coronavirus disease 2019, can enter the brain. Severe acute respiratory syndrome coronavirus 2 binds to cells via the S1 subunit of its spike protein. We show that intravenously injected radioiodinated S1 (I-S1) readily crossed the blood–brain barrier in male mice, was taken up by brain regions and entered the parenchymal brain space. I-S1 was also taken up by the lung, spleen, kidney and liver. Intranasally administered I-S1 also entered the brain, although at levels roughly ten times lower than after intravenous administration. APOE genotype and sex did not affect whole-brain I-S1 uptake but had variable effects on uptake by the olfactory bulb, liver, spleen and kidney. I-S1 uptake in the hippocampus and olfactory bulb was reduced by lipopolysaccharide-induced inflammation. Mechanistic studies indicated that I-S1 crosses the blood–brain barrier by adsorptive transcytosis and that murine angiotensin-converting enzyme 2 is involved in brain and lung uptake, but not in kidney, liver or spleen uptake.


Pfizer/BioNTech animal trials show dangerous concentrations of nano-particles in organs


A study from Nature Neuroscience showed that the S1 spike protein of SARS-CoV-2 crosses the blood–brain barrier in mice, causing damage to the cardiovascular and central nervous systems. The spike protein ended up in the peripheral tissues – thus SARS-CoV-2 RNA was recovered from cerebrospinal fluid.

The study showed that these new spike proteins exploit angiotensin-converting enzyme 2 (ACE2), allowing for increased intake of spike proteins into the lungs and specifically to the brain. This is how SARS-CoV-2 manifests in the central nervous system, which include changes to taste and smell, headaches, twitching, seizures, confusion, vision impairment, nerve pain, dizziness, impaired consciousness, nausea, hemiplegia, ataxia, stroke and cerebral hemorrhage.

Spike proteins readily cross the blood-brain barrier through a process called adsorptive transcytosis. Inflammation notably increases spike protein uptake in the brain and lungs. And when the animals were induced with inflammation, the intravenously-administered spike proteins entered the brain more readily.
lol mice
 

SoldierMan

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Are you @Hamster? That report is based on rats...

And? We've always done it that way.

Google
Mice have many advantages over other model organisms: Their genome is similar to the human genome (99%), a good genetic/molecular toolbox is available and the animal's small size facilitates large scale/high throughput studies making it a cost-efficient model.

Mice as Models to Study Human Disease: Hereditary Deafness
The identification of genes responsible for hereditary deafness provides an excellent example of the utility of mice for studying human disorders.
 

quovadis

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Spike proteins readily cross the blood-brain barrier through a process called adsorptive transcytosis. Inflammation notably increases spike protein uptake in the brain and lungs. And when the animals were induced with inflammation, the intravenously-administered spike proteins entered the brain more readily.
Lol. Do you note the glaring measure? Intravenously-administered spike proteins and induced inflammation?
 

Conack

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Are you @Hamster? That report is based on rats...

https://apnews.com/article/fact-checking-afs:Content:9792931264 :

The Pfizer and Moderna vaccines are mRNAs vaccines that skipped animal trials because using mRNA vaccines on animals triggers dangerous inflammation.
Due to the urgent need for a vaccine in a surging pandemic, Pfizer and Moderna were given approval to simultaneously test their vaccines on animals while they were conducting Phase 1 trials on humans. The vaccines were tested on mice and macaques.


1626705234076.png
 
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