One thing about eye evolution is the genetic machinery and circuitry needed for its development. One animal that I find fascinating is the Trichoplax adhaerens. Here you have an animal that looks like a flattened blob with only four cell types. There are no nerve cells, sensory cells, muscle cells, bone cells etc. It is an animal at the base of the eukaryotic evolutionary tree .
Several types of eyes exist and these include the camera-type eye, the compound eye, and the mirror eye. Ernst Mayr proposed that eyes evolved in all animal phyla 40 to 60 times independently (maybe even more).
A monophyletic program governing the development of the different eye types is proposed and the Pax6 gene is posited to be the master control gene. The Pax6 gene also plays a part in controlling the development of the nose, ears and parts of the brain.
What is needed for the developmental program of eyes?
A few core genes include:
Pax6 (eyeless [eye]) in Drosophila)
Six-type genes (E.g. Six3)
Sox-type genes (E.g. Sox2)
atonal ( E.g. Atoh7)
Retinoid receptors
Fox transcription factors (E.g. FoxN4)
Pitx
Fascinating experiments have been conducted by shuffling around the genetic program architecture of genes associated with eye development in various animals.
For example in Drosophila:
Ectopic eye structures are able to be induced on the antennae, legs, and wings of fruit flies. This is done by targeted expression of the eyeless gene (Pax6 Drosophila homologue) (Figure 2). The Pax6 gene from the mouse is able to do the same job as the Drosophila version (Figure 3). And in Xenopus embryos, ectopic eye structures in can also be induced by the Drosophila eyeless (Pax6) version (Figure 4).
What about the Trichoplax adhaerens genome? Any genes for eye development?
It seems quite a chunk of the circuitry needed for eye development is present. (
From table 1)
PaxB (eyeless?)
Six genes
Sox gene
Atonal gene
Retinoid X Receptor
Fox transcription factors
Pitx
So, large chunks of the circuitry for eye development was present in Trichoplax way before the eye even emerged.
The same is true for the development of
multicellularity.