Russo-Ukrainian War - 2022 Edition - Part 4

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Nicodeamus

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I think he's talking about accummulated mutations in successive generations of offspring. Knocking out anti-oncogenes can have effects further down the line. If your gametes are injured those errors will be passed on to further generations. Oncogenesis is a multi-step process.

That doesn't occur at low dose radiation..... the basis for it is the LNT model....


The LNT model is justified based on the assumption that DNA damage and mutations are caused by even very low levels of radiation and increased mutations would result in increased cancers, using the somatic mutation model of cancer. Both of these notions underlying the LNT model have turned out to be wrong.2 Whereas there would be an increase in DNA damage shortly after exposure to low-dose radiation (LDR, there would also be enhanced bodily defenses such as increased production of antioxidants and DNA repair enzymes, collectively referred to as adaptive protection.3

Because of the boosted defenses, there would be less of the naturally occurring DNA damage in the subsequent period, with the net result being reduced overall DNA damage and mutations following exposure to LDR.2 Also, there is plenty of evidence against the mutation model of cancer.2 Thus, since the two concepts underlying the LNT model are not valid, the model is not justifiable. Hence, the concept of ALARA, which is based on the LNT model, should not be used in medical imaging, considering that medical imaging involves LDR exposures only.
 

Paulsie

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I think he's talking about accummulated mutations in successive generations of offspring. Knocking out anti-oncogenes can have effects further down the line. If your gametes are injured those errors will be passed on to further generations. Oncogenesis is a multi-step process.
It's called sarcasm. And he should be more specific. But either way, he has absolutely no proof for his opinion.

He just likes to make wild long term predictions, like everybody with covid who's unvaccinated will suffer serious health issues later on in their lives.

He is the one who always asks for proof yet NEVER provides one himself.
 

Paulsie

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Russia claimed Ukraine is shelling them. Russia must prove this.
The claim was satellites can track shelling. Russia is accused of endangering the NP due to shelling, yet no pictures are available.

One side blames the other; it should be so easy to prove.
 

Nicodeamus

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It's called sarcasm. And he should be more specific. But either way, he has absolutely no proof for his opinion.

He just likes to make wild long term predictions, like everybody with covid who's unvaccinated will suffer serious health issues later on in their lives.

He is the one who always asks for proof yet NEVER provides one himself.

He falls back on authority, because he doesn't have the ability or willingness to attempt to understand the literature.
 

Mirai

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Nicodeamus

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I see disagreement in letters to an editor I don't see any established facts. I also don't see this being applied to every possible scenario in Ukraine.

the debate in the literature is if the LNT model is valid. We actually know that there is good evidence to suggest that it is wrong.
It's applicable to Ukraine given that the background radiation at Chernobyl is about the same as Ramsar in Iran and other places where people live with elevated levels.
 

Mirai

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It's called sarcasm. And he should be more specific. But either way, he has absolutely no proof for his opinion.

He just likes to make wild long term predictions, like everybody with covid who's unvaccinated will suffer serious health issues later on in their lives.

He is the one who always asks for proof yet NEVER provides one himself.

I don't think anyone ever claimed all unvaccinated people would face serious health issues.
 

Nicodeamus

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I don't think anyone ever claimed all unvaccinated people would face serious health issues.

it was claimed that the vaccine will protect you, after 4 boosters and multiple reinfections it should be clear as daylight that it was one fat lie.

Remember this nugget from the CDC?
 

Mirai

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the debate in the literature is if the LNT model is valid. We actually know that there is good evidence to suggest that it is wrong.

OK there is good evidence you claim to suggest it is wrong. To suggest and good evidence. This is not enough to claim it is wrong.

It's applicable to Ukraine given that the background radiation at Chernobyl is about the same as Ramsar in Iran and other places where people live with elevated levels.

SPECULATION.
 

Nicodeamus

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OK there is good evidence you claim to suggest it is wrong. To suggest and good evidence. This is not enough to claim it is wrong.



SPECULATION.


There is no good evidence, the uncertainty lies in what the limit should be. The "fallback is the LNT model that we know is conservative, yet wrong" i.e. it has a safety factor.
 
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