A truck carrying more than 100 bodies was stopped on the N2 near Somerset West on Saturday afternoon.
Police spokesperson Colonel Andre Traut confirmed police officers were currently on the scene to investigate the incident.
"We are probing the circumstances under which the corpses were being transported," Traut said.
According to information, traffic officials stopped and searched the truck at the N2 weigh bridge near Somerset Mall and found 106 bodies, believed to be Covid-19 victims, inside.
The Western Cape health department says it is awaiting final confirmation on whether the more than 100 corpses found in a truck that was stopped at a weighbridge in Somerset West were those of people who died of Covid-19.