I have never ran out of fuel. I have put family members on standby after having an emergency unplanned trip of 300Km on quater tank of fuel and still made it.
Currently still 1 mark above half in my honda with 345Km on the Trip counter. computer estimates more than 400Km left in tank. Little 1500cc Vtec. with 30 liter tank.
Also driving with an empty tank makes you consume less as you are carrying less weight. Combine that with a Decent diet and all is well.