With seemingly no one interested in buying Twitter, the company is left with only tough choices, Reuters reported.
These include: major restructuring, cutting staff, or risk facing activist investors.
In recent years, investors have aggressively pushed US companies to implement better cash management, leadership changes, and new strategies, said Reuters.
This warning comes after the news earlier this month that Twitter had approached banks to look at selling itself.
According to reports, Salesforce, Walt Disney, and Google looked at buying Twitter, but decided against it.
The company has been plagued by an inability to turn large profits in recent years, which has further aggravated investors.