{"id":425450,"date":"2021-11-30T13:27:21","date_gmt":"2021-11-30T11:27:21","guid":{"rendered":"https:\/\/mybroadband.co.za\/news\/?p=425450"},"modified":"2021-11-30T13:27:52","modified_gmt":"2021-11-30T11:27:52","slug":"self-replicating-xenobot-breakthrough","status":"publish","type":"post","link":"https:\/\/mybroadband.co.za\/news\/science\/425450-self-replicating-xenobot-breakthrough.html","title":{"rendered":"Self-replicating xenobot breakthrough"},"content":{"rendered":"<p>The US scientists that created the world&#8217;s first living robots, dubbed Xenobots, have now discovered that they can reproduce in a way that has not been observed in any other organism, CNN <strong><a href=\"https:\/\/edition.cnn.com\/2021\/11\/29\/americas\/xenobots-self-replicating-robots-scn\/index.html\" target=\"_blank\" rel=\"noopener\">reported<\/a><\/strong>.<\/p>\n<p>According to the <strong><a href=\"https:\/\/www.pnas.org\/content\/118\/49\/e2112672118\" target=\"_blank\" rel=\"noopener\">study&#8217;s<\/a><\/strong> lead author, Josh Bongard, the xenobots use &#8220;kinetic replication&#8221; \u2014 a process known to occur at a molecular level but had never been seen before in whole cells or organisms.<\/p>\n<p>The C-shaped parent xenobots collect and compress loose stem cells together into piles which can mature into offspring.<\/p>\n<p>Research co-lead Michael Levin is a biology professor and director of the Allen Discovery Centre at Tufts University.<\/p>\n<p>\u201cFrogs have a way of reproducing that they normally use,\u201d CNN quoted Levin as saying.<\/p>\n<p>&#8220;But when you liberate [the cells] from the rest of the embryo, and you give them a chance to figure out how to be in a new environment, not only do they figure out a new way to move, but they also figure out apparently a new way to reproduce.&#8221;<\/p>\n<p>Created from stem cells of the African clawed frog (<em>Xenopus laevis<\/em>)\u00a0and initially revealed in 2020, early experiments showed that xenobots could move, work together, and self-heal.<\/p>\n<p>To create the xenobots, researchers took live stem cells from frog embryos and left them to incubate.<\/p>\n<p>&#8220;In that way, it&#8217;s a robot, but it&#8217;s also clearly an organism made from genetically unmodified frog cells,&#8221; Bongard said.<\/p>\n<p>Using artificial intelligence (AI), the research team tested different body shapes to improve the efficiency of xenobot replication \u2014 which previously happened rarely and only in specific situations.<\/p>\n<p>Their testing found that a C-shape\u2014reminiscent of Pacman\u2014was the most efficient shape.<\/p>\n<p>They found it could to find hundreds of stem cells in a petri dish and collect them inside its &#8220;mouth&#8221;.<\/p>\n<p>The bundle formed by the parent xenobot would then develop over a few days to create offspring.<\/p>\n<p>While this is still early technology and doesn&#8217;t have any practical uses yet, the intersection of AI and molecular biology could potentially be used in various tasks, both in the body and the environment.<\/p>\n<p>&#8220;There are many things that are possible if we take advantage of this kind of plasticity and ability of cells to solve problems,&#8221; Bongard said.<\/p>\n<hr \/>\n<h3 class=\"my-4\">Now read: <a href=\"https:\/\/mybroadband.co.za\/news\/science\/425030-why-south-africa-gets-so-many-covid-19-variants-of-concern.html\" target=\"_blank\" rel=\"noopener\">Why South Africa gets so many Covid-19 variants of concern<\/a><\/h3>\n","protected":false},"excerpt":{"rendered":"<p>US researchers have discovered that biological &#8220;robots&#8221; replicate in a way that has never been observed in whole cells or organisms.<\/p>\n","protected":false},"author":341076,"featured_media":425452,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[31750],"tags":[74718,74724,74720,20571,74722],"class_list":["post-425450","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","tag-josh-bongard","tag-living-robots","tag-michael-levin","tag-stem-cell-research","tag-xenobot"],"_links":{"self":[{"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/posts\/425450"}],"collection":[{"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/users\/341076"}],"replies":[{"embeddable":true,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/comments?post=425450"}],"version-history":[{"count":1,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/posts\/425450\/revisions"}],"predecessor-version":[{"id":425464,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/posts\/425450\/revisions\/425464"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/media\/425452"}],"wp:attachment":[{"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/media?parent=425450"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/categories?post=425450"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/tags?post=425450"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}