{"id":448072,"date":"2022-06-09T13:56:11","date_gmt":"2022-06-09T11:56:11","guid":{"rendered":"https:\/\/mybroadband.co.za\/news\/?p=448072"},"modified":"2022-06-09T13:58:52","modified_gmt":"2022-06-09T11:58:52","slug":"scientists-create-functional-3d-printed-heart-component","status":"publish","type":"post","link":"https:\/\/mybroadband.co.za\/news\/science\/448072-scientists-create-functional-3d-printed-heart-component.html","title":{"rendered":"Scientists create functional 3D-printed heart component"},"content":{"rendered":"<p>Researchers from Harvard University&#8217;s Wyss Institute have developed a method to 3D-print a functional component of the human heart, Engadget <strong><a href=\"https:\/\/www.engadget.com\/3-d-printed-functional-heart-piece-191938833.html\" target=\"_blank\" rel=\"noopener\">reported<\/a><\/strong>.<\/p>\n<p>The technique allowed researchers to create functional long cardiac macrofilaments that develop into muscle-like filaments that can contract.<\/p>\n<p>The Wyss Institute has leveraged bioprinting for some time, and the new technique is a refined version of its SWIFT (Sacrificial Writing in Functional Tissue) technology.<\/p>\n<p>The new methodology included creating a platform of a little over 1,000 wells, each featuring two microscopic columns.<\/p>\n<p>After that, the team fills each well with human-induced pluripotent stem cells \u2014 or immature cells capable of evolving into various forms \u2014 a protein collagen, and connective tissue cells.<\/p>\n<div id=\"attachment_448080\" style=\"width: 810px\" class=\"wp-caption aligncenter\"><a  data-lightbox=\"post-image\" href=\"https:\/\/mybroadband.co.za\/news\/wp-content\/uploads\/2022\/06\/3D-printing-technique-for-heart-componentV.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-448080\" class=\"wp-image-448080 size-full\" src=\"https:\/\/mybroadband.co.za\/news\/wp-content\/uploads\/2022\/06\/3D-printing-technique-for-heart-componentV.jpg\" alt=\"\" width=\"800\" height=\"748\" srcset=\"https:\/\/mybroadband.co.za\/news\/wp-content\/uploads\/2022\/06\/3D-printing-technique-for-heart-componentV.jpg 800w, https:\/\/mybroadband.co.za\/news\/wp-content\/uploads\/2022\/06\/3D-printing-technique-for-heart-componentV-428x400.jpg 428w, https:\/\/mybroadband.co.za\/news\/wp-content\/uploads\/2022\/06\/3D-printing-technique-for-heart-componentV-570x533.jpg 570w, https:\/\/mybroadband.co.za\/news\/wp-content\/uploads\/2022\/06\/3D-printing-technique-for-heart-componentV-768x718.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/a><p id=\"caption-attachment-448080\" class=\"wp-caption-text\">3D bioprinting technique. Image: <strong><a href=\"https:\/\/wyss.harvard.edu\/news\/getting-to-the-heart-of-engineering-a-heart\/\" target=\"_blank\" rel=\"noopener\">Wyss Institute at Harvard University<\/a><\/strong>.<\/p><\/div>\n<p>A dense tissue then forms, and the team lifts the organ constituent off the microscopic pillars, and it is then used as bioprinting ink.<\/p>\n<p>The 3D-printed cardiac tissue constructs have high cellular densities typical of normal heart tissue.<\/p>\n<p>The project&#8217;s senior author, Jennifer Lewis, explained the benefits of the new technology.<\/p>\n<p>&#8220;Being able to effectively mimic the alignment of the heart&#8217;s contractile system across its entire hierarchy from individual cells to thicker cardiac tissue composed of multiple layers is central to generating functional heart tissue for replacement therapy,&#8221; she <strong><a href=\"https:\/\/wyss.harvard.edu\/news\/getting-to-the-heart-of-engineering-a-heart\/\" target=\"_blank\" rel=\"noopener\">said<\/a><\/strong>.<\/p>\n<p>While this is a significant development, there is still much work before researchers can create a fully-functional 3D-printed heart.<\/p>\n<hr \/>\n<h3 class=\"my-4\">Now read: <a href=\"https:\/\/mybroadband.co.za\/news\/science\/447844-carmaker-geely-puts-first-satellites-into-space.html\" target=\"_blank\" rel=\"noopener\">Carmaker Geely puts first satellites into space<\/a><\/h3>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at Harvard University&#8217;s Wyss Institute managed to bioprint functional long cardiac macrofilaments.<\/p>\n","protected":false},"author":341076,"featured_media":448078,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[31750],"tags":[17542,78950,78948,32560],"class_list":["post-448072","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","tag-3d-printing","tag-3d-printed-organs","tag-bioprinting","tag-harvard-university"],"_links":{"self":[{"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/posts\/448072"}],"collection":[{"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/users\/341076"}],"replies":[{"embeddable":true,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/comments?post=448072"}],"version-history":[{"count":1,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/posts\/448072\/revisions"}],"predecessor-version":[{"id":448164,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/posts\/448072\/revisions\/448164"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/media\/448078"}],"wp:attachment":[{"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/media?parent=448072"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/categories?post=448072"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mybroadband.co.za\/news\/wp-json\/wp\/v2\/tags?post=448072"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}