The results seem to be mixed but mostly unsuccessful as detailed in the SA MCE "Any success with Remote Learning on Multichoice PVR decoder ?" thread.TivoZA - Do you know of anyone who has managed to change the DSTV PVR channels with the MCE remote?
Since the Pronto CCF codes are available, this problem is really limited to MCE users as most other software is able to make use of the Pronto codes. The "USB-UIRT Users" thread describes how you should (in theory) be able to make use of the Pronto codes in MCE but nobody has confirmed if this method works.