What?
no dude.
that question makes no sense at all.
Google uses JS themeselves for analitics, so google can read JS.
what are you trying to do? your question is so open ended it makes no sense at all.
if you are using AJax to load content pages based on what is clicked then sure it wont be indexed correctly. but why would you even do that? this makes no sense...
If that was the case then google wouldn't be able to index a big portion of the web - which it clearly can do.