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Tweak Guides said:[Engine.GameEngine]
CacheSizeMegs=32
This value represents the amount of System RAM set aside for temporarily caching game information. This setting is not designed to impact on FPS as such, it is more for reducing loading pauses in-game. You can try a cache size of 64 or 128, however I don't suggest increasing this value any higher since the cache is not where the entire game can load into. In general given that BioShock is relatively smooth, altering this value will likely have no major impact on stuttering, but try raising it if you do notice stuttering.
[WinDrv.WindowsClient]
WindowedViewportX=1024
WindowedViewportY=768
These settings control the resolution of the game when run in Windowed mode. In case something prevents you from changing them in-game after a crash for example, alter them here.
FullscreenViewportX=1280
FullscreenViewportY=1024
These settings control the resolution of the game when run in fullscreen mode, and can be adjusted within the game. However if you want to try a custom resolution change the X (width) and Y (height) values above accordingly.