Can I ask for a few basics:
Hassio on Pi or Windows/Linux with Docker - I am assuming docker.
Windows/Linux - any Firewall issues?
Anything updated e.g. watchtower did an auto update on Docker?
Did you import any flows with an HA node in there? It imports that HA server config as well and you end up with the second one as well which could be messing up your config.
Is the HA config in Node Red pointing directly to the IP or are you going via DuckDNS?
Have you defined the trusted networks in configuration.yaml?
YAML:
auth_providers:
- type: trusted_networks
trusted_networks:
- 127.0.0.0/24
- 172.17.0.0/16
- 192.168.1.0/24