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I ran the installer over Leopard as well with no issues. Like Gambit said, a couple of apps will need updates. You might want to install an app like AppFresh http://metaquark.de/appfresh it'll scan your machine for all the apps that need updating and you can download and install them from the app as well.
Don't forget to backup, you can always restore from a Timemachine backup if something goes wrong, it helped me a great deal.Great thanks a lot, I will give that a try.