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We configure 9014 as our frame size as far as Jumbo Frames are concerned, specifically on storage-related interfaces. This includes the iSCSI interfaces, as it was pointed out, as well as any and all Live Migration/vMotion interfaces.
You have to have JF configured on your SAN if you have virtual machines residing on it, purely because of the size of the data. If you don't you will have stipid high latency, and you will run into performance issues on your VMs.
EDIT> Remember that the same MTU needs to be configured on the network side to make things happen.
Have you done the config on your switches as well?