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Postfix is your SMTP server.This tutorial shows how to prepare an Ubuntu 11.10 (Oneiric Ocelot) server for the installation of ISPConfig 3, and how to install ISPConfig 3. ISPConfig 3 is a webhosting control panel that allows you to configure the following services through a web browser: Apache web server, Postfix mail server, MySQL, BIND or MyDNS nameserver, PureFTPd, SpamAssassin, ClamAV, and many more.
Source: http://www.howtoforge.com/perfect-server-ubuntu-11.10-ispconfig-3
Postfix is your SMTP server.
ISPConfig provides a web based gui to configure everything.
thanks guys! I installed CENTOS and using webmin. Seems to be working well. I'm using sendmail and can send mail directly from the server. Just havent figured out how to configure pop3 yet!