Topics and discussions relevant to Natural Sciences

DrJohnZoidberg

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Jul 24, 2006
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Well, the way I see it, astrophysics is a sub-field or branch of astronomy but I just don't see astronomy itself as being covered by Physics, Chemistry or Earth Sciences, and definitely not one of the Life Sciences as listed in the OP.

http://en.wikipedia.org/wiki/Astrophysics also mentions it as a branch of astronomy. (Again with the caveat that Wikipedia is not the source of absolute facts or definitions)

http://en.wikipedia.org/wiki/Natural_sciences Also lists astronomy under natural sciences. First, in fact.

Cool, let's add an astronomy to the list, its pretty obvious for that to be included.
 

DrJohnZoidberg

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Jul 24, 2006
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While I agree that some aspects of ontology are intrinsically philosophical, I disagree that it is necessarily so.

Biologically ontologies (e.g. Gene Ontology - GO) are practically very much relevant. I make use of it almost on a weekly basis. We work with large information sets of gene and protein expression and without GO and the GO-related software it would virtually be impossible to analyse the data. GO is of course not perfect and it is constantly being improved and is intrinsically relevant to many areas of the biological sciences.

I don't know enough on the subject to understand all the complexities but I think for a field like this which is being physically applied it makes sense to include it.

I just want to avoid arguments that stem from "why's" which don't have answers that can be scientifically reasoned.
 

Techne

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Sep 28, 2008
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Pretty cool drug that PA-824.
PA-824 Kills Nonreplicating Mycobacterium tuberculosis by Intracellular NO Release
The mechanism of action of PA-824

Have they discovered the specific protein it binds to that are relevant to its activity? Any resolved crystal structures so far?

EDIT: Ooh, found it 3R5R :D

I am sure we can get people here involved to find a more potent South African analogs...using freely available computational chemistry software :)...
 
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