Understanding medical research

Thanks for the link. I agree, the basics and steps of medical research needs to be understood.

Often popular articles allude to promising results in pre-clinical studies, e.g. in vitro studies, or animal studies. Fascinating as it sounds, the proof of concept only comes when stage III clinical trials (at least) are completed. Before that, a massive amount of work needs to be done, e.g. mechanistic studies, pharmacokinetics, safety etc.
 
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