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Durability is not an issue, this pc probably gets used 3 times a week for short durations without any heavy workloads.
Until something happens that the average user can't recover from... Ransomware for example will end up encrypting all the files you've synced as well.
(Though I'll admit I don't know as much about the new "Backup and Sync" app, I haven't used Windows at all since that came out so I'm not sure how well it works.)
If you're a power user you can work around this sort of thing but there are still gotchas for the average Joe.