Again, it is folly to claim that something is not possible just because it is beyond our current capabilities and understanding.
You are assuming a whole stack of things in your assumption that the brain's architecture cannot be provided for digitally. For example, that the hardware involved will closely resemble today's consumer hardware, that our understanding of how the brain works will not improve exponentially, that the human mind is more than just the sum of the brain's physical parts, that the need for external stimuli cannot be provided for in a virtual environment etc.
Any conclusion that relies on a host of potentially false assumptions is fairly meaningless. When discussing the long term future of humanity, I think it's good to bear in mind Arthur C Clarke's "any sufficiently advanced technology is indistinguishable from magic". Can you imagine the gibberish that people 1+ centuries ago must have theorised about the state of the world in our time period?