No doubt. People will look at EvE, sure, but most will find it...unsavoury. It's too different, and even with the new tutorials, it's still difficult to wrap your head around it. Understanding EvE takes time. Most people are too impatient to scale that curve.whoever hits now with a big and nice MMO will take it.
There are a glut of potential WoW killers in the making. I doubt any of them will really make a dent - I like the idea of Champions Online - building my own superhero is too cool and i missed the whole CoH craze - but it probably won't make it big, at least nowhere near WoW.
There is but one possible dethroner, imo.
Star Wars.