After an hour you wont even care about the effects any more, it's so minuscule in the greater scheme of things. You'll end up far more focused on actually playing to care about such a small thing. I find it so silly to write the game off because you don't get effect A or B, an effect that makes no difference to your enjoyment of the game whatsoever.
The fact of the matter is that the game developer chose to make the game look better using an nvidia graphics card. The physX part of it can easily be emulated if necessary.
I'll be cancelling my pre-order as a matter of principle. As I said as well, this will be no major loss for me as I have too many games to play right now anyway.