-1 for Symantec.
The various Nortons became steadily more bloated from when I first started using them in 96' till they became absolute resource hogs without actually doing much. Switched to AVG and haven't looked back. I have endpoint protection on my work PC and got one of those autorun viruses, updated and couldn't get rid of it, finally managed to delete it myself cause Symantec couldn't find it. AGV found it easily every time I plugged a drive into my home PC. I managed to get rid of it myself and disabled autorun so it doesn't bother me, thing is endpoint protection still can't find it, this is something AVG has been catching since January. Utterly worthless piece of software. If I'd paid for it I'd be demanding my money back and if my company would let me I'd get rid of it and install something else.
On a side note, has anyone ever had heuristic protection catch a legitimate virus without having definitions. I have had warnings from heuristic software when installing legit software but it's never sniffed out a reaal virus.
Gonna try MSE though, sounds worthwhile.