How about: let's discuss cholesterol

If you are lean and metabolically healthy but experience a significant increase in LDL cholesterol levels on a low carb diet , you may be classified as a lean hyper-responder. David Feldman, a researcher and engineer who has extensively studied lipid metabolism and cholesterol, has coined this term. His research on this topic has been influential in understanding how some individuals can be more susceptible to LDL cholesterol increases, even if they are lean and metabolically healthy.

Cholesterol Code — Reverse Engineering the Mystery

Cholesterol Code by Dave Feldman — explore the documentary and the research archive.
cholesterolcode.com

It's seems I'm one of them.
 
There are several biomarkers that can indicate metabolic health. Here are some examples:
  1. Blood sugar levels: Fasting blood glucose levels and HbA1c levels are important markers of metabolic health. Normal fasting glucose levels should be below 100 mg/dL, while HbA1c levels should be below 5.7%.
  2. Insulin sensitivity: Insulin resistance is a key feature of metabolic dysfunction, so measuring insulin sensitivity can be useful. The gold standard test is a euglycemic-hyperinsulinemic clamp test, but other simpler tests include the HOMA-IR (homeostatic model assessment of insulin resistance) or fasting insulin levels.
  3. Lipid profile: A lipid profile measures various types of cholesterol and triglycerides in the blood. Metabolically healthy individuals generally have low levels of triglycerides, high levels of HDL.
  4. Inflammatory markers: Chronic inflammation is a hallmark of metabolic dysfunction, so measuring inflammatory markers such as CRP, TNF-alpha, and IL-6 can be useful
 
While magnesium is not a cure-all for heart disease, it is an important nutrient that can help support heart health.

Magnesium is an essential mineral that plays a crucial role in various bodily functions, including nerve and muscle function, bone health, and heart health. It has been shown to have a positive impact on lipid profiles, including lowering triglycerides and increasing high-density lipoprotein cholesterol (HDL-C).

Additionally, magnesium has been shown to have beneficial effects on blood clotting, plaque formation, and inflammation, all of which are key factors in the development of heart disease.

Good food sources for magnesium is Avocado and wild Salmon. Dark chocolate is also a good option but I'm a bit conserned about heavy metals in them.
 
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If anyone wants to go into the details, I recommend listening to the podcasts of Andrew Huberman. He has one on Cholesterol and there is also a podcast with Dr Peter Attie that also addresses the details on cholesterol. It tends to go into extreme scientific details and what I also like is they are willing to state when science doesn't know the answer .
 
BBSA said:
The conclusion that high triglycerides and low HDL is a must better indication of impaired metabolism and poor health than you LDL level.
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The thing is, without knowing the credentials of the author and your own, it is hard to say how accurate it is.
TheMightyQuinn said:
Indeed! I've also "known" this for many years.

The people most uninformed about cholesterol seems to be GP's...
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I have found that GPs (and medical professionals) know a lot more than the general public think they do. Whenever I see something I think is new that affects me, my doctors already know about it and address it.
I think what gives some people the impressions that medical professionals have outdated information, is that they wait for more studies and don't latch on to everything they read on the internet.

When speaking to my (quite old) GP about my cholesterol, he always said not to worry since my HDL was high, that cholesterol was important, and if I want to lower my overall cholesterol I should concentrate more on exercise than reducing fatty foods. This was a decade ago.

Personal anecdote - my overall cholesterol level has been dropping steadily after upping my egg intake to an average of 2 per day and reduced my carb intake. Last time I checked it was finally under 5. (personal anecdotes are not medical advice - speak to your doctor)
 
Barbarian Conan said:
The thing is, without knowing the credentials of the author and your own, it is hard to say how accurate it is.
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That's a fair point, and it's always wise to do your own research before making any conclusions. In fact, several doctors have come to similar conclusions, and one of them is Dr. Paul Mason. If you're interested, you're welcome to check out his credentials.
 
My GP didn't want to use meds to treat my cholesterol. Rather control the Diabetes + Hypothyroidism and also pushing me to exercise and eat properly. Regular exercise seems to work on the cholesterol levels nicely.
 
Informed consent is an important ethical principle in medical practice, and it is particularly important when prescribing long-term medication like statins. Patients have the right to know the benefits and risks of any medication they are taking, as well as alternative treatment options.

The process of obtaining informed consent involves discussing the treatment options with the patient, including the potential benefits and risks of the medication. The healthcare provider should also explain any possible side effects or adverse reactions, as well as any potential interactions with other medications the patient may be taking.

This right is often neglected by our healthy care providers.
 
BBSA said:
Informed consent is an important ethical principle in medical practice, and it is particularly important when prescribing long-term medication like statins. Patients have the right to know the benefits and risks of any medication they are taking, as well as alternative treatment options.

The process of obtaining informed consent involves discussing the treatment options with the patient, including the potential benefits and risks of the medication. The healthcare provider should also explain any possible side effects or adverse reactions, as well as any potential interactions with other medications the patient may be taking.

This right is often neglected by our healthy care providers.
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Had low testosterone a while back, doc was very happy to try and get me onto treatment, but didn't stop once to discuss that trt is a lifelong treatment. You cannot stop it randomly. Too high a dose has mayor side effects, and if you do decide to stop treatment, there is a high likelihood that your testosterone drops below where you started.

I payed for the consultation, and left.
Right then and there I turned my eating / sleeping and exercise habits around. No trt needed.

We all make terrible decisions. I gave 15 years to a job that was not worth 2 years. I gave my time to people who got rich (I mean millionaire) off my long hours. At one point I worked 72 hours non-stop per week for a month. I sacrificed my health, strength and time in the hopes that I could carve something long lasting for myself.

It nearly killed me.

Look after your health, once it's gone, or slipping away, it takes a herculean effort to restore it.
 
Although most of his videos are quite long, very interesting tests he does on himself with bloodwork results before and after.
Very interesting!



 
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Check the glucose goddess, she provides science behind her statements (she’s a biochemist).
 
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