garyc
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If the pitch of the sound also changes when you move the mouse or open a window then you probably have what is called blitter noise. This tends to be caused by an interaction between the graphics card and the sound card. Being an interaction on the board this can get complicated.
The first thing to do is check the electrical grounding, as others have suggested. Bear in mind that the computer and it's power lead are not the only potential source of ground loops. The ground also runs through your signal cable to the monitor and the power cable to the monitor. Unplug these two cables one at a time and see if that effects the noise.
Next check is to see if the PSU voltages are within range.
If none of this works then it gets complicated. One thing to try will be to update both the sound and graphics drivers.
The first thing to do is check the electrical grounding, as others have suggested. Bear in mind that the computer and it's power lead are not the only potential source of ground loops. The ground also runs through your signal cable to the monitor and the power cable to the monitor. Unplug these two cables one at a time and see if that effects the noise.
Next check is to see if the PSU voltages are within range.
If none of this works then it gets complicated. One thing to try will be to update both the sound and graphics drivers.