Bar0n
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Charles Babbage. He was quite comfortable. So comfortable he turned down lands and titles.
Jenner too. Successful doctor.
Louis Pasteur didn't want for much (though his wealth mostly came from his discoveries, he was born relatively poor, still he was wealthy no denying that).
Isaac Newton too. He actually ran the royal mint at one point. A position that paid an obscene amount of money.
Those are just off the top of my head. I'm surprised you aren't aware of any wealthy scientists pre 1900.
However, the vast majority were poor. Many of them died at a young age due to poverty and disease (and the occasional romantic mathematician, who died for a girl).