Unless you now what you're doing with a registry, I'd steer clear of reg cleaners like CCleaner.
Win10 has some nifty ways to refresh a PC without losing data or programs.
And if you must start again, why not rather invest in a decent disk imaging program like Acronis (
Home version bundle,
Corporate version): Set up your standard installation and make a disk image. When things go wonky, simply restore the image in minutes. The restore is clean and sectors are contiguous (so fully defragged). I keep a master image of a fresh install with all apps, and whenever important system updates or changes are made, I made a new image. Never reinstall Windows again.