So after trying not to play until the weekend, I fired this puppy up for 30 mins or so, just to see what it was like.
My specs are in my signature, but I have a R9280X and an i5 4570. Running in 2560x1440, with most settings on high, AA on SSAO, water, world detail and one other I forget on Ultra, with hairworks on everything that has them, not just Geralt.
I definitely get noticable FPS drops in the in-game cutscenes, but gameplay seems perfect for now. I have only gotten as far as the Tavern section (did the tutorials to familiarise myself again)... I'll post more once I've ventured further out, but hope it stays the same as it is now.
Apparently, there is a 30fps cap on cutscenes.
See https://www.reddit.com/r/witcher/comments/36jn8s/psa_how_to_fix_30fps_cut_scenes_and_fov_work/
for a workaround. Haven't tried it myself though.

