Played for about 1.5 hours today so far. I have it on the PC. Mixed feelings really.
I am considering getting my PS3 controller and some third party software to get it to work, just to see if it is any smoother. The KB and Mouse is pretty horrible in the menus. Opening up the wagon wheel is very ugly. The 4 main points (Up, Down,Left,Right) are all pretty easy to hit with the mouse controller, but the 4 diagonal points are like trying to thread a needle with a bulldozer.
So far, I don't really care about hacking the single mom, diagnosed with cancer. Because the profiler finds someone to hack and I hack em. The game has notoriety, but that is for your "in the light" actions. Hacking a good person from the shadows and taking their life savings has zero impact it seems, except to make me feel like a dick. Which obviously doesn't happen because I am robbing pixels. If taking money from people via hacks, had some kind of in game effect, then I might feel something.
Still got plenty to do though. I will play a bit more before deciding whether the story is worth it to pursue.