Once again, same issue again tonight being reported by me and my friends on Afrihost in the Western Cape region.
For the past two nights, it seems to start happening around 7:15pm to 7:30pm, particularly with YouTube.
Popular videos with large viewer counts are loading content fine (due to local caching) but as soon as you try to view a Live video or video with a low view count (sourced from international servers), it just doesn't load at all.
I posted a screenshot already last night of YouTube's "stats for nerds" where it shows a stable fast connection (I'm on 20mbps) but no content is actually loading into the aforementioned types of videos.
I repeat, if I or other people reporting the same issue use a diffrent ISP it works. Go back to Afrihost, then the issue persists. So it's a problem on your network that connects to international servers.