Depression.

Well.

Was feeling like a zombie. Lowered my dose of medication. Now I don't feel like a zombie, but absolutely miserable. There are not really words to describe what this, to borrow a word from Terry Pratchett, embuggerance does to you.

Ugh.

As a friend said to me this afternoon: 'you are a lifer, get used to it'.

The thought of having to use medication for whatever remains of my life mortifies me. Ideally, I'd have access to a mental health professional. My medical aid though, scoffs at the notion that depression and the like are conditions worthy of spending coin on.

Any how.

Update. **** one.

Meh.
 
Watched a documentary called "Food Matters" last night on Netflix. A guy on there said that high doses of Niacin is very effective against depression. Think they were talking about 1500mg or even higher per day. Any of you guys know about this? Tried it?

This documentary seems to be the main source of this claim. I'd be extraordinarily careful about taking this sort of suggestion seriously, without a fair whack of supporting evidence.
 
This documentary seems to be the main source of this claim. I'd be extraordinarily careful about taking this sort of suggestion seriously, without a fair whack of supporting evidence.

I think this comes from the work of Abram Hoffer.

Edit: Yes it does... Btw he used it in alcoholism as well.

http://www.doctoryourself.com/hoffer_niacin.html
http://www.doctoryourself.com/niacinreviews.html

I found it beneficial a few years ago, but found it was drying out my eyes.
 
I think this comes from the work of Abram Hoffer.

Edit: Yes it does... Btw he used it in alcoholism as well.

http://www.doctoryourself.com/hoffer_niacin.html
http://www.doctoryourself.com/niacinreviews.html

I found it beneficial a few years ago, but found it was drying out my eyes.

Reading up on Hoffer doesn't fill me much confidence. I don't mean to say he's a nut or anything (don't have enough info at my disposal), but a cursory glance doesn't convince me of the validity of the claim being made here. I just think caution/further investigation is good when taking unusually large amount of anything, especially seeking a benefit that is tenuous.
 
Reading up on Hoffer doesn't fill me much confidence. I don't mean to say he's a nut or anything (don't have enough info at my disposal), but a cursory glance doesn't convince me of the validity of the claim being made here. I just think caution/further investigation is good when taking unusually large amount of anything, especially seeking a benefit that is tenuous.

I was only pointing you to where the niacin treatment came from...
 
Not that I am aware of.

I guess you could always look for a sympathetic vet.

:erm:

That's a shame. Sounds revolutionary for sufferers of depression. You'd think more facilities would push hard to get on board.
 
:erm:

That's a shame. Sounds revolutionary for sufferers of depression. You'd think more facilities would push hard to get on board.

I'm under the impression that there's been a bit of excited media hysteria over Ketamine, as opposed to sober clinical investigation (with regards to depression).

I'm all for it, in a general sense, but we need to be cautious and responsible and above all we need more data.

*edit*

I'd try it, personally. But, as to be expected, if you are in an area where this sort of treatment is available it's going to cost a pretty penny...
 
For those interested in Ketamine, there are currently tests on compounds that act via the same pathway.

CGP3466B
NRX-1074 For anyone interested, there is currently a group buy with spots open. No - I'm not part of it.
GLYX-13

Related to topic, but using a different pathway
NSI-189

I don't have depression myself, but these compounds's neuroprotective and possible nootropic effects interest me.
 
I'm under the impression that there's been a bit of excited media hysteria over Ketamine, as opposed to sober clinical investigation (with regards to depression).

I'm all for it, in a general sense, but we need to be cautious and responsible and above all we need more data.

*edit*

I'd try it, personally. But, as to be expected, if you are in an area where this sort of treatment is available it's going to cost a pretty penny...

Yeah. Unfortunately it doesn't look like simple oral medication atm.
 
Does Ketamine depression treatment exist in SA yet?

Yes, it does. Ketamine is fully licensed by the MCC. The treatment can be done as a day patient with an infusion pump. As a medication, ketamine is relatively inexpensive.

I know of a few psychiatrists in Cape Town that are already delivering this intervention, and am keen to start doing so myself.
 
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